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PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE
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DeCS
Descriptor
English
:
Pituitary Adenylate Cyclase-Activating Polypeptide
Descriptor
Spanish
:
Polipéptido Hipofisario Activador de la Adenilato-Ciclasa
Descriptor
Portuguese
:
Polipeptídeo Hipofisário Ativador de Adenilato Ciclase
Tree Number:
D12.644.276.860.887
D12.644.400.625
D12.776.467.860.887
D12.776.641.600.887
D12.776.641.650.625
D23.529.850.887
Definition
English
:
A multi-function neuropeptide that acts throughout the body by elevating intracellular
cyclic AMP
level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the
control
of endocrine and homeostatic processes, such as secretion of pituitary and gut
hormones
and
food
intake.
Pharmacological Action:
Growth Substances
Neurotransmitter Agents
Vasodilator Agents
History Note
English
:
2006(1990)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
50569
Unique Identifier:
D051219
Occurrence in VHL
:
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